منابع مشابه
The analgesic efficacy of celecoxib, pregabalin, and their combination for spinal fusion surgery.
BACKGROUND As optimal pain relief after surgery is difficult to achieve with the use of just one drug, many pain experts advocate the use of two or more classes of medications so as to reduce the side effects from any one drug. In this trial, we assessed the analgesic efficacy of administering perioperative celecoxib, pregabalin, or both after spinal fusion surgery. METHODS Eighty patients sc...
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WHAT IS KNOWN AND OBJECTIVE Based on in vitro assays and select animal models, buprenorphine is commonly called a 'partial agonist'. An implication is that it should produce less analgesic effect in humans than so-called 'full agonists' such as morphine or fentanyl. However, buprenorphine has a multimechanistic pharmacology, and thus partial agonism at a specific receptor is not particularly re...
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Diclofenac and paracetamol (acetaminophen) are either pain relievers, or analgesics, and can reduce fevers. They differ in numerous ways, however, such as in their drug classification and strength. Consumers will find other differences between these drugs in their ease of access to them, and the types of side effects or warnings that accompany them. Moreover, one or the other of these medicatio...
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The objective of this study was to quantify the analgesic efficacy of paracetamol and its combination with codeine or caffeine through a systematic overview and meta-analysis of relevant randomized controlled trials (RCTs). Systematic retrieval of relevant clinical trials was carried out using computerized searches, historical searches and communication with manufacturers. The results of RCTs w...
متن کاملAnalgesic and Decongestant Efficacy of the Combination of Aspirin with Pseudoephedrine in Patients With Symptoms of Upper Respiratory Tract Infection
The study investigated the efficacy and safety of a combination therapy of 1,000 mg aspirin (ASA) and 60 mg pseudoephedrine (PSE) on the symptoms of pain (combined score for headache and sore throat) and nasal congestion in 833 patients with acute upper respiratory tract viral infection (URTI), over 4 hours after a single dose in the clinic and over 3 days with multiple doses at home. The study...
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ژورنال
عنوان ژورنال: Journal of Pain and Symptom Management
سال: 2002
ISSN: 0885-3924
DOI: 10.1016/s0885-3924(01)00404-3